Krechetov Sergey, biophysics, biochemistry, biomechanics, toxicology, pharmacology, cosmetics, mathematical modeling, locomotion, cell, stem cell, fibroblast, amoeba, toxicity, biological activity, sensibility, mechanism of action, prognosis, TCDD, dioxin, lewisite, mustard gas, chemical weapons, cytohrome P450, reactive oxygen species, lipid peroxidation, dispersion, nanodispersion, emulsion, nanoemulsion, liposomes, drug, delivery system
Main
Research interests

 

Publications
Over 130 publications

Recent publications

Articles

Rembovskiy V.R., Krechetov S.P., Gerashenko V.M. [Toxicometric principles of delimitation of health protection areas after incidents on the chemical weapons destruction facilities]// Ross. Khim. Zhurn. (Zhurn. Ross. Khim. ob-va im. D.I. Mendeleeva), 2010.-V.54.-4.-P.85-88. Russian. PDF
[Interspecies and line variation in death time following poisoning by substances with different involvement of lipid peroxidation in the mechanism of toxic action]/ Alimov N.I., Rembovskiy V.R., Krechetov S.P., Popovich V.I., Gerashenko V.M.// Toksikol. vestnik, 2007.-.4.-P.13-23. Russian. PDF
[Inter- and intraspecies differences in lipid peroxidation and in characteristics of pro and antioxidant systems in experimental mammalian]/ Alimov N.I., Rembovskiy V.R., Krechetov S.P., Popovich V.I., Gerashenko V.M.// Toksikol. vestnik, 2005.-.5.-P.13-23. Russian.PDF
[Impact of particularities of lipid peroxidation and the state of pro and antioxidant systems on susceptibility of laboratory mammals to biologically active substances]/ Alimov N.I., Rembovskiy V.R., Krechetov S.P., Popovich V.I., Gerashenko V.M.// Toksikol. vestnik, 2005.-.4.-P.6-12. Russian. PDF
[Inter- and intraspecies variation of susceptibility of biota to substances with different involvement of lipid peroxidation in the mechanism of toxic action]/ Alimov N.I., Rembovskiy V.R., Krechetov S.P., Popovich V.I., Gerashenko V.M.// Toksikol. vestnik, 2005.-.2.-P.14-22. Russian.PDF
Rembovskiy V.R., Krechetov S.P., Gerashenko V.M. [Pathobiochemical mechanism of 2,3,7,8 tetrachlorodibenzo p dioxin (TCDD) action.] Doklady Akademii Voennyh nauk. Series "Applied problems of chemical weapons decomposition and military ecology".-2000.- 6.-P.149-162. Russian.PDF
Krechetov S.P. [Statistical perspectives of biological objects parameters changes revealing after action of low effective doses of toxic substances.] Doklady Akademii Voennyh nauk. Series "Applied problems of chemical weapons decomposition and military ecology".-2000.- 6.-P.109-116. Russian.PDF

Monographs

[Legislative regulation of therapeutic and preventive nutrition of workers under harmful and especially harmful labour conditions]/ Izmerova N.I., Kuzmina L.P., Pilat .L., Istimin .V., Krechetov S.P., Mokina .N., Koliaskina ..// .: Research Institute of Occupational Health of RAMS, 2009.-51 p. Russian. PDF

Conferences

Smolaninov V.V., Krechetov S.P. [Correlation of susceptibility to bioactive substance with parameters of biological objects as base for prognosis of individual and group human toxicometry parameters of toxic substances]// Proceedings of 6th International Scientific and Practical Congress Man in Extreme Condition: Human Factor and Professional Health, 13-17 October 2008.- Moscow, 2008, P.263-264. Russian.PDF
Smolaninov V.V., Krechetov S.P., [Software and hardware system for biomechanical human cardiac pulse investigations with ability of autonomic registration]// Proceedings of 6th International Scientific and Practical Congress Man in Extreme Condition: Human Factor and Professional Health, 13-17 October 2008.- Moscow, 2008, P.36-37. Russian.PDF
Krechetov S.P., Rembowsky V.R., Gerashenko V.M. Prooxidative shift in toxic action of TCDD. Proceedings of 11th SAC Seminar New Trends in Chemical Toxicology, 22-25 September 2008.- Moscow, 2008, P.63.PDF, Poster PDF
Krechetov S.P., Oksinojd O.E., Maevskij E.I. Cellular transport mechanisms in action of colloidal delivery systems. Proceedings of International Symposium Biological Motility dedicated to the memory of academician G.M. Frank (1904-1976), May 23-June 1 2008.- Pushchino, 2008, P.175-176.PDF, Poster PDF
Krechetov S.P., Smolaninov V.V. Experimental estimation of fibroblasts forced deformations invariants. Proceedings of International Symposium Biological Motility dedicated to the memory of academician G.M. Frank (1904-1976), May 23-June 1 2008.- Pushchino, 2008, P.226-227.PDF
Ahsyanov U.U., Oksinoid O.E., Krechetov S.P., Schelokova O.S. [Perspectives of multilevel disperse systems use as delivery systems of active components in cosmetics.] Proceedings of XI International Scientific Practical Conference Cosmetic Products and Row Materials: Safety and Efficacy 24-26 October 2006.- Moscow, 2006, P.48-49. Russian. PDF(RU), PDF(ENG), PPT.
Smolaninov V.V., Krechetov S.P., [Hardware and software system for biomechanical monitoring of human cardiac pulse]// Proceedings of 5th International Scientific and Practical Congress Man in Extreme Condition: Health, Reliability and rehabilitation, 16-20 October 2006.- Moscow, 2006, P.34-37. Russian.PDF(RU).
Krechetov S.P., Smolaninov V.V. Investigation of fibroblast biomechanics by micropipette aspiration technique. International Symposium Biological Motility: Basic Research and Practice, May 11-15 2006.- Pushchino, 2006, P.153-154.PDF, PPT
Ahsyanov U.U., Oksinoid O.E., Krechetov S.P., Maevskiy E.I., Chebotar' I.V., Muhina I.V. [Multilevel disperse systems in cosmetics.] Proceedings of X International Scientific Practical Conference Cosmetic Products and Row Materials: Safety and Efficacy 7-9 2005.- Moscow, 2005, P.55-56. Russian.PDF(RU), PDF(ENG), PPT
Rumyancev K.A., Kalugin I.Yu., Krechetov S.P., Smolyaninov V.V. [Parameterization of mechanopulsograms in diagnostics of cardio-vascular system state.] Proceedings of 9-th All-Russian Scientific and Technical Conference State and Problems of Measurements 2325 November 2004.- Moscow, 2004.- .118-119. Russian.PDF
Krechetov S.P., Smolyaninov V.V. [Multipoint monitoring of cardio-vascular system functional state.] Proceedings of 9-th All-Russian Scientific and Technical Conference State and Problems of Measurements 2325 November 2004. Moscow, 2004.- .117. Russian.PDF, PPT
Ahsyanov U.U., Parnev O.M., Oksinoid O.E., Krechetov S.P., Maevskiy E.I., Hizhnyak E.P., Hizhnyak L.N. [The complex approach in creation of multifunctional cosmetic.] Proceedings of IX International Scientific Practical Conference Cosmetic Products and Row Materials: Safety and Efficacy 25 27 October 2004.- Moscow, 2004.- P.38. Russian.PDF(RU), PDF(ENG), PPT
Rumyancev K.A., Krechetov S.P., Rakcheeva T.A., Smolyaninov V.V., Yavelov I.S. [Parametric variability of mechanopulsograms.] Proceedings of Russia III Biophysical Congress, 24 29 June 2004 Voronez.- Voronez, 2004.- .373-374. Russian.PDF
Krechetov S.P., Smolyaninov V.V. [Mechanical properties of A. proteus in locomotion.] Proceedings of Russia III Biophysical Congress, 24 29 June 2004 Voronez.- Voronez, 2004.- .347 348. Russian.PDF, PPT
Krechetov S.P., Smolaninov V.V. Surface structure movement related to locomotion of A. proteus. International Symposium Biological Motility dedicated to the memory of academician G.M. Frank (1904-1976), May 23-June 1 2004.- Pushchino, 2004, P.175-176.PDF, PPT
Krechetov S.P. [Pathobiochemical basis of lipid peroxidation intensification on treatment of high-toxic inductors of cytochrome P 450.] Proceedings of Scientific Conference 40 years MBF RGMU 20-21 November 2003.- Moscow, 2003. Russian.HTML, PDF

Patents and patent applications

Patent application RF 2012102815; Filed: 30.01.2012. Russian. HTML
Int. Appl. WO 2012166008 A1 IPC A61K 31/05 (2006.01), A61K 31/12 (2006.01), A61K 31/155 (2006.01), A61K 31/165 (2006.01), A61K 31/216 (2006.01), A61K 31/352 (2006.01), A61K 31/353 (2006.01), A61K 31/37 (2006.01), A61K 31/375 (2006.01), A61K 31/44 (2006.01), A61K 36/74 (2006.01), A61K 45/06 (2006.01), A61P 3/10 (2006.01). Combination for treatment of diabetes mellitus/ Leshkov, S.Y.; Vikhrieva, N.S.; Krechetov, S.P.- Appl. No. PCT/RU2012/000254; Filed 05.04.2012; Publ. 06.12.2012.PDF
Patent RF 2451506 C1 Int. Cl. A61K31/05 (2006.01), A61K31/35 (2006.01), A61P3/10 (2006.01). Combination for treatment of diabetes and complications thereof/ S.J. Leshkov, N.S. Vikhrieva, S.P. Krechetov.- 2011122374/15, Filed 02.06.2011; Publ. 27.05.2012, Bull. 15.PDF
Patent RF 2437692 C2 Int. Cl. A61N5/10 (2006.01), A61N5/067 (2006.01), A61M16/12 (2006.01), A61K31/02 (2006.01), A61K31/455 (2006.01), A61K31/196 (2006.01), A61K35/14 (2006.01), A61K35/28 (2006.01), A61P35/00 (2006.01), B82B1/00 (2006.01). Method of treating solid malignant growths and their metastases/ S.J. Leshkov, N.S. Vikhrieva, S.P. Krechetov.- N 2010109034/14; Filed 12.03.2010; Publ. 27.12.2011 Bull. 36. Russian.PDF
Patent RF 2381792 C2, Int. Cl. A61K31/02 (2006.01), A61K8/04 (2006.01), A61Q19/08 (2006.01). [Preparation for mesotherapy]/ U.U. Ahsyanov, O.E. Oksinoid, S.P. Krechetov, E.I. Maevskiy, E.K. Fomina.- N 2008112524/15; Appl. 02.04.2008; Publ. 10.10.2009, Bull. N 28. Russian.PDF
Patent RF 2304960 , Int. Cl. A61K 8/97 (2006.01), A61K 8/891 (2006.01), A61K 8/19 (2006.01), A61K 8/44 (2006.01), A61K 8/67 (2006.01). [Cosmetic agent for skin application]/ U.U. Ahsyanov, O.E. Oksinoid, S.P. Krechetov, O.M. Parnev, E.I. Maevskiy.- N 2005130520/15; Appl. 03.10.2005; Publ. 27.08.2007, Bull. N 10. Russian.PDF
Patent RF 2304959 , Int. Cl. A61K 8/97 (2006.01), A61K 8/70 (2006.01), A61K 8/64 (2006.01), A61K 8/24 (2006.01). [Cosmetic preparation that protects skin against disorders initiated by active and passive smoking (variants) and oxygen-transporting multiple nanoemulsion being the constituent of its composition (variants).]/ U.U. Ahsyanov, O.E. Oksinoid, S.P. Krechetov, O.M. Parnev, L.A. Makhlis.- N 2005130518/15; Appl. 03.10.2005; Publ. 27.08.2007, Bull. N 10. Russian.PDF
Patent RF 2299060 1, Int. Cl. A61K 8/891 (2006.01), A61K 8/04 (2006.01), A61K 8/24 (2006.01), A61Q 19/00 (2006.01). [Organosilicone emulsion for cosmetic and/or dermatological agents, method for production thereof and cosmetic agent]/ U.U. Ahsyanov, O.E. Oksinoid, S.P. Krechetov, O.M. Parnev, E.I. Maevskiy, E.V. Grishina.- N 2005130520/15; Appl. 03.10.2005; Publ. 20.05.2007, Bull. N 14. Russian. PDF
Patent RF 2296558 1, Int. Cl. A61K 8/891 (2006.01), A61K 8/19 (2006.01), A61Q 19/00 (2006.01). [Emulsion of organosilicones for cosmetic and/or dermatological agents and method for production thereof]/ U.U. Ahsyanov, O.E. Oksinoid, S.P. Krechetov, O.M. Parnev.- N 2005130519/15; Appl. 03.10.2005; Publ. 10.04.2007, Bull. N 10. Russian. PDF

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Krechetov 2012